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ECST-2 investigators; Donners SJA, van Velzen TJ, Cheng SF, Gregson J, Hazewinkel AD, Pizzini FB, Emmer BJ, Simister R, Richards T, Lyrer PA, Maurer M, Smith G, Tervit G, van der Steen L, Pickett GE, Gubitz G, Roozenbeek B, Scheele M, Bamford JM, Kooi ME, de Borst GJ, Jäger HR, Brown MM, Nederkoorn PJ, Bonati LH Optimised medical therapy alone versus optimised medical therapy plus revascularisation for asymptomatic or low-to-intermediate risk symptomatic carotid stenosis (ECST-2): 2-year interim results of a multicentre randomised trial Lancet Neurol. 2025 May;24(5):389-399. doi: 10.1016/S1474-4422(25)00107-3