Citation Select	INTERACT Investigators; Wang X, Ren X, Li Q, Ouyang M, Chen C, Delcourt C, Chen X, Wang J, Robinson T, Arima H, Ma L, Hu X, You C, Li G, Jie Y, Lin Y, Billot L, Muñoz-Venturelli P, Martins S, Pontes-Neto OM, Liu L, Chalmers J, Carcel C, Song L, Anderson CS Effects of blood pressure lowering in relation to time in acute intracerebral haemorrhage: a pooled analysis of the four INTERACT trials Lancet Neurol. 2025 Jul;24(7):571-579. doi: 10.1016/S1474-4422(25)00160-7
Citation Select	ECST-2 investigators; Donners SJA, van Velzen TJ, Cheng SF, Gregson J, Hazewinkel AD, Pizzini FB, Emmer BJ, Simister R, Richards T, Lyrer PA, Maurer M, Smith G, Tervit G, van der Steen L, Pickett GE, Gubitz G, Roozenbeek B, Scheele M, Bamford JM, Kooi ME, de Borst GJ, Jäger HR, Brown MM, Nederkoorn PJ, Bonati LH Optimised medical therapy alone versus optimised medical therapy plus revascularisation for asymptomatic or low-to-intermediate risk symptomatic carotid stenosis (ECST-2): 2-year interim results of a multicentre randomised trial Lancet Neurol. 2025 May;24(5):389-399. doi: 10.1016/S1474-4422(25)00107-3
Citation Select	EXPECTS Group; Yan S, Zhou Y, Lansberg MG, Liebeskind DS, Yuan C, Yu H, Chen F, Chen H, Zhang B, Mao L, Zhang X, Wang X, Zhang X, Chen Y, Zhou H, Zhong W, He Y, Chen K, Wang J, Chen H, Huang Y, Campbell BCV, Lou M Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours N Engl J Med. 2025 Apr 3;392(13):1288-1296. doi: 10.1056/NEJMoa2413344
Citation Select	PRESTIGE-AF Consortium; Veltkamp R, Korompoki E, Harvey KH, Harvey ER, Fießler C, Malzahn U, Rücker V, Montaner J, Caso V, Sibon I, Ringleb P, Halse O, Hügen K, Ullmann S, Schuhmann C, Todd GP, Haas K, Palà E, Debette S, Lachaize M, D,Aoust T, Enzinger C, Ropele S, Fandler-Höfler S, Haidegger M, Wang Y, Wafa HA, Cancelloni V, et al Direct oral anticoagulants versus no anticoagulation for the prevention of stroke in survivors of intracerebral haemorrhage with atrial fibrillation (PRESTIGE-AF): a multicentre, open-label, randomised, phase 3 trial Lancet. 2025 Mar 15;405(10482):927-936. doi: 10.1016/S0140-6736(25)00333-2
Citation Select	Writing Committee for the PERSIST Collaborators; Khan F, Yogendrakumar V, Lun R, Ganesh A, Barber PA, Lioutas VA, Vinding NE, Algra A, Weimar C, Ögren J, Edwards JD, Swartz RH, Ois A, Giralt-Steinhauer E, Khanevski AN, Leng X, Tian X, et al. Long-Term Risk of Stroke After Transient Ischemic Attack or Minor Stroke: A Systematic Review and Meta-Analysis JAMA. 2025 Mar 26:e252033. doi: 10.1001/jama.2025.2033. Epub ahead of print
Citation Select	TRACE-III Investigators; Xiong Y, Campbell BCV, Schwamm LH, Meng X, Jin A, Parsons MW, Fisher M, Jiang Y, Che F, Wang L, Zhou L, Dai H, Liu X, Pan Y, Duan C, Xu Y, Xu A, Zong L, Tan Z, Ye W, Wang H, Wang Z, Hao M, Cao Z, Wang L, Wu S, Li H, Li Z, Zhao X, Wang Y Tenecteplase for Ischemic Stroke at 4.5 to 24 Hours without Thrombectomy N Engl J Med. 2024 Jun 14. doi: 10.1056/NEJMoa2402980. Epub ahead of print
Citation Select	LASTE Trial Investigators; Costalat V, Jovin TG, Albucher JF, Cognard C, Henon H, Nouri N, Gory B, Richard S, Marnat G, Sibon I, Di Maria F, Annan M, Boulouis G, Cardona P, Obadia M, Piotin M, Bourcier R, Guillon B, Godard S, Pasco-Papon A, Eker OF, Cho TH, Turc G, Naggara O, Velasco S, Lamy M, Clarençon F, Alamowitch S, Renu A, Suissa L, Brunel H, Gentric JC, Timsit S, Lamy C, Chivot C, Macian-Montoro F, Mounayer C, Ozkul-Wermester O, Papagiannaki C, Wolff V, Pop R, Ferrier A, Chabert E, Ricolfi F, Béjot Y, Lopez-Cancio E, Vega P, Spelle L, Denier C, Millán M, Arenillas JF, Mazighi M, Houdart E, Del Mar Freijo M, Duhamel A, Sanossian N, Liebeskind DS, Labreuche J, Lapergue B, Arquizan C Trial of Thrombectomy for Stroke with a Large Infarct of Unrestricted Size N Engl J Med. 2024 May 9;390(18):1677-1689. doi: 10.1056/NEJMoa2314063
Citation Select	ATAMIS investigators; Chen HS, Cui Y, Wang XH, Ma YT, Han J, Duan YJ, Lu J, Shen LY, Liang Y, Wang WZ, Wang H, Zhao Y, Zhang JT, Song YL, He XM, Li RH, Tao DB, Li J, Huang SM, Wang N, Hong M, Meng C, Zhang W, Wang DL, Nguyen TN Clopidogrel Plus Aspirin vs Aspirin Alone in Patients With Acute Mild to Moderate Stroke: The ATAMIS Randomized Clinical Trial JAMA Neurol. 2024 Mar 11:e240146. doi: 10.1001/jamaneurol.2024.0146. Epub ahead of print
Citation Select	TIMELESS Investigators; Albers GW, Jumaa M, Purdon B, Zaidi SF, Streib C, Shuaib A, Sangha N, Kim M, Froehler MT, Schwartz NE, Clark WM, Kircher CE, Yang M, Massaro L, Lu XY, Rippon GA, Broderick JP, Butcher K, Lansberg MG, Liebeskind DS, Nouh A, Schwamm LH, Campbell BCV Tenecteplase for Stroke at 4.5 to 24 Hours with Perfusion-Imaging Selection N Engl J Med. 2024 Feb 22;390(8):701-711. doi: 10.1056/NEJMoa2310392
Citation Select	INSPIRES Investigators; Gao Y, Chen W, Pan Y, Jing J, Wang C, Johnston SC, Amarenco P, Bath PM, Jiang L, Yang Y, Wang T, Han S, Meng X, Lin J, Zhao X, Liu L, Zhao J, Li Y, Zang Y, Zhang S, Yang H, Yang J, Wang Y, Li D, Wang Y, Liu D, Kang G, Wang Y, Wang Y Dual Antiplatelet Treatment up to 72 Hours after Ischemic Stroke N Engl J Med. 2023 Dec 28;389(26):2413-2424. doi: 10.1056/NEJMoa2309137
Citation Select	CATIS-2 Investigators; Liu L, Xie X, Pan Y, Wang A, Wei Y, Liu J, Nie X, Liu D, Zhao Z, Wang P, Shen S, Zhong C, Xu T, Wang D, Wang GC, Song D, Ma Y, Zhao J, Jiang Y, Jing J, Meng X, Obst K, Chen CS, Wang D, Wang Y, Zhang Y, Wang Y, He J Early versus delayed antihypertensive treatment in patients with acute ischaemic stroke: multicentre, open label, randomised, controlled trial BMJ. 2023 Oct 9;383:e076448. doi: 10.1136/bmj-2023-076448
Citation Select	Cai H, Chen G, Hu W, Jiang C Anticoagulant in atrial fibrillation patients with prior intracranial haemorrhage: a meta-analysis Heart. 2023 Jun 15:heartjnl-2023-322492. doi: 10.1136/heartjnl-2023-322492. Epub ahead of print
Citation Select	ANGEL-ASPECT Investigators ; Huo X, Ma G, Tong X, Zhang X, Pan Y, Nguyen TN, Yuan G, Han H, Chen W, Wei M, Zhang J, Zhou Z, Yao X, Wang G, Song W, Cai X, Nan G, Li D, Wang AY, Ling W, Cai C, Wen C, Wang E, Zhang L, Jiang C, Liu Y, Liao G, Chen X, Li T, Liu S, Li J, Gao F, Ma N, Mo D, Song L, Sun X, Li X, Deng Y, Luo G, Lv M, He H, Liu A, Zhang J, Mu S, Liu L, Jing J, Nie X, Ding Z, Du W, Zhao X, Yang P, Liu L, Wang Y, Liebeskind DS, Pereira VM, Ren Z, Wang Y, Miao Z Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct N Engl J Med. 2023 Feb 10. doi: 10.1056/NEJMoa2213379
Citation Select	SELECT2 Investigators ; Sarraj A, Hassan AE, Abraham MG, Ortega-Gutierrez S, Kasner SE, Hussain MS,Chen M, Blackburn S, Sitton CW, Churilov L, Sundararajan S, Hu YC, Herial NA, Jabbour P, Gibson D, Wallace AN, Arenillas JF, Tsai JP, Budzik RF, Hicks WJ, Kozak O, Yan B, Cordato DJ, Manning NW, Parsons MW, Hanel RA, Aghaebrahim AN, Wu TY, Cardona-Portela P, Pérez de la Ossa N, Schaafsma JD, Blasco J, Sangha N, Warach S, Gandhi CD, Kleinig TJ, Sahlein D, Elijovich L, Tekle W, Samaniego EA, Maali L, Abdulrazzak MA, Psychogios MN, Shuaib A, Pujara DK, Shaker F, Johns H, Sharma G, Yogendrakumar V, Ng FC, Rahbar MH, Cai C, Lavori P, Hamilton S, Nguyen T, Fifi JT, Davis S, Wechsler L, Pereira VM, Lansberg MG, Hill MD, Grotta JC, Ribo M, Campbell BC, Albers GW Trial of Endovascular Thrombectomy for Large Ischemic Strokes N Engl J Med. 2023 Feb 10. doi: 10.1056/NEJMoa2214403
Citation Select	Cochrane A, Chen C, Stephen J, Rønning OM, Anderson CS, Hankey GJ, Al-Shahi Salman R Antithrombotic treatment after stroke due to intracerebral haemorrhage Cochrane Database Syst Rev. 2023 Jan 26;1(1):CD012144. doi: 10.1002/14651858.CD012144.pub3
Citation Select	Oldgren J, Åsberg S, Hijazi Z, Wester P, Bertilsson M, Norrving B; National TIMING Collaborators Early Versus Delayed Non-Vitamin K Antagonist Oral Anticoagulant Therapy After Acute Ischemic Stroke in Atrial Fibrillation (TIMING): A Registry-Based Randomized Controlled Noninferiority Study Circulation. 2022 Oct 4;146(14):1056-1066. doi: 10.1161/CIRCULATIONAHA.122.060666
Citation Select	BAOCHE Investigators; Jovin TG, Li C, Wu L, Wu C, Chen J, Jiang C, Shi Z, Gao Z, Song C, Chen W, Peng Y, Yao C, Wei M, Li T, Wei L, Xiao G, Yang H, Ren M, Duan J, Liu X, Yang Q, Liu Y, Zhu Q, Shi W, Zhu Q, Li X, Guo Z, Yang Q, Hou C, Zhao W, Ma Q, Zhang Y, Jiao L, Zhang H, Liebeskind DS, Liang H, Jadhav AP, Wen C, Brown S, Zhu L, Ye H, Ribo M, Chang M, Song H, Chen J, Ji X Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion N Engl J Med. 2022 Oct 13;387(15):1373-1384. doi: 10.1056/NEJMoa2207576
Citation Select	Tao C, Nogueira RG, Zhu Y, Sun J, Han H, Yuan G, Wen C, Zhou P, Chen W, Zeng G, Li Y, Ma Z, Yu C, Su J, Zhou Z, Chen Z, Liao G, Sun Y, Ren Y, Zhang H, Chen J, Yue X, Xiao G, Wang L, Liu R, Liu W, Liu Y, Wang L, Zhang C, Liu T, Song J, Li R, Xu P, Yin Y, Wang G, Baxter B, Qureshi AI, Liu X, Hu W; ATTENTION Investigators Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion N Engl J Med. 2022 Oct 13;387(15):1361-1372. doi: 10.1056/NEJMoa2206317
Citation Select	Chen X, Liu F, Lin S, Yu L, Lin R Effects of Virtual Reality Rehabilitation Training on Cognitive Function and Activities of Daily Living of Patients With Poststroke Cognitive Impairment: A Systematic Review and Meta-Analysis Arch Phys Med Rehabil. 2022 Jul;103(7):1422-1435. doi: 10.1016/j.apmr.2022.03.012
Citation Select	Tsivgoulis G, Triantafyllou S, Palaiodimou L, Grory BM, Deftereos S, Köhrmann M, Dilaveris P, Ricci B, Tsioufis K, Cutting S, Magiorkinis G, Krogias C, Schellinger PD, Dardiotis E, Rodriguez-Campello A, Cuadrado-Godia E, Aguiar de Sousa D, Sharma M, Gladstone DJ, Sanna T, Wachter R, Furie KL, Alexandrov AV, Yaghi S, Katsanos AH Prolonged Cardiac Monitoring and Stroke Recurrence: A Meta-analysis Neurology. 2022 May 10;98(19):e1942-e1952. doi: 10.1212/WNL.0000000000200227
Citation Select	RESTART Collaboration; Al-Shahi Salman R, Dennis MS, Sandercock PAG, Sudlow CLM, Wardlaw JM, Whiteley WN, Murray GD, Stephen J, Rodriguez A, Lewis S, Werring DJ, White PM Effects of Antiplatelet Therapy After Stroke Caused by Intracerebral Hemorrhage: Extended Follow-up of the RESTART Randomized Clinical Trial JAMA Neurol. 2021 Oct 1;78(10):1179-1186. doi: 10.1001/jamaneurol.2021.2956
Citation Select	CHANCE-2 Investigators; Wang Y, Meng X, Wang A, Xie X, Pan Y, Johnston SC, Li H, Bath PM, Dong Q, Xu A, Jing J, Lin J, Niu S, Wang Y, Zhao X, Li Z, Jiang Y, Li W, Liu L, Xu J, Chang L, Wang L, Zhuang X, Zhao J, Feng Y, Man H, Li G, Wang B Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA N Engl J Med. 2021 Dec 30;385(27):2520-2530. doi: 10.1056/NEJMoa211174
Citation Select	Buck BH, Hill MD, Quinn FR, Butcher KS, Menon BK, Gulamhusein S, Siddiqui M, Coutts SB, Jeerakathil T, Smith EE, Khan K, Barber PA, Jickling G, Reyes L, Save S, Fairall P, Piquette L, Kamal N, Chew DS, Demchuk AM, Shuaib A, Exner DV Effect of Implantable vs Prolonged External Electrocardiographic Monitoring on Atrial Fibrillation Detection in Patients With Ischemic Stroke: The PER DIEM Randomized Clinical Trial JAMA. 2021 Jun 1;325(21):2160-2168. doi: 10.1001/jama.2021.6128
Citation Select	Bhatia K, Jain V, Aggarwal D, Vaduganathan M, Arora S, Hussain Z, Uberoi G, Tafur A, Zhang C, Ricciardi M, Qamar A Dual Antiplatelet Therapy Versus Aspirin in Patients With Stroke or Transient Ischemic Attack: Meta-Analysis of Randomized Controlled Trials Stroke. 2021 Jun;52(6):e217-e223. doi: 10.1161/STROKEAHA.120.033033
Citation Select	AREST Investigators; Labovitz AJ, Rose DZ, Fradley MG, Meriwether JN, Renati S, Martin R, Kasprowicz T, Murtagh R, Kip K, Beckie TM, Stoddard M, Bozeman AC, McTigue T, Kirby B, Tran N, Burgin WS Early Apixaban Use Following Stroke in Patients With Atrial Fibrillation: Results of the AREST Trial Stroke. 2021 Apr;52(4):1164-1171. doi: 10.1161/STROKEAHA.120.030042
Citation Select	THALES Investigators; Johnston SC, Amarenco P, Denison H, Evans SR, Himmelmann A, James S, Knutsson M, Ladenvall P, Molina CA, Wang Y Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA N Engl J Med. 2020 Jul 16;383(3):207-217. doi: 10.1056/NEJMoa1916870
Citation Select	Dennis M, Forbes J, Graham C, Hackett M, Hankey GJ, House A, Lewis S, Lundström E, Sandercock P, Mead G Fluoxetine to improve functional outcomes in patients after acute stroke: the FOCUS RCT Health Technol Assess. 2020 May;24(22):1-94. doi: 10.3310/hta24220
Citation Select	Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, Biller J, Brown M, Demaerschalk BM, Hoh B, Jauch EC, Kidwell CS, Leslie-Mazwi TM, Ovbiagele B, Scott PA, Sheth KN, Southerland AM, Summers DV, Tirschwell DL Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update. A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association Stroke. 2019 Dec;50(12):e344-e418
Citation Select	Anadani , Arthur , Tsivgoulis , Simpson , Alawieh , Orabi , Goyal , Alexandrov , Maier , Psychogios , Liman , Brinton , Swisher , Shah , Inamullah , Keyrouz , Kansagra , Allen , Giles , Wolfe , Fargen , Gory , De Marini , Kan , Nascimento , Almallouhi , Petersen , Kodali , Rahman , Richard , Spiotta , Blood Pressure Goals and Clinical Outcomes after Successful Endovascular Therapy: A Multicenter Study Ann Neurol. 2020 Mar 18. doi: 10.1002/ana.25716. [Epub ahead of print]
Citation Select	Rahman H, Khan SU, Nasir F, Hammad T, Meyer MA, Kaluski E Optimal Duration of Aspirin Plus Clopidogrel After Ischemic Stroke or Transient Ischemic Attack Stroke. 2019 Apr;50(4):947-953
Citation Select	Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ, Kim AS, Lindblad AS, Palesch YY; Clinical Research Collaboration, Neurological Emergencies Treatment Trials Network, and the POINT Investigators Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA N Engl J Med. 2018 Jul 19;379(3):215-225. doi: 10.1056/NEJMoa1800410
Citation Select	Hart Sharma Mundl Kasner Bangdiwala Berkowitz Swaminathan Lavados Wang Wang Davalos Shamalov Mikulik Cunha Lindgren Arauz Lang Czlonkowska Eckstein Gagliardi Amarenco Ameriso Tatlisumak Veltkamp Hankey Toni Bereczki Uchiyama Ntaios Yoon Brouns Endres Muir Bornstein Ozturk O,Donnell De Vries Basson Pare Pater Kirsch Sheridan Peters Weitz Peacock Shoamanesh Benavente Joyner Themeles Connolly NAVIGATE ESUS Investigators Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source N Engl J Med. 2018 06 07;378(23):2191-2201
Citation Select	Albers Marks Kemp Christensen Tsai Ortega-Gutierrez McTaggart Torbey Kim-Tenser Leslie-Mazwi Sarraj Kasner Ansari Yeatts Hamilton Mlynash Heit Zaharchuk Kim Carrozzella Palesch Demchuk Bammer Lavori Broderick Lansberg DEFUSE 3 Investigators Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging N Engl J Med. 2018 02 22;378(8):708-718
Citation Select	DAWN Trial Investigators; Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA, Hassan AE, Millan M, Levy EI, Mitchell P, Chen M, English JD, Shah QA, Silver FL, Pereira VM, Mehta BP, Baxter BW, Abraham MG, Cardona P, Veznedaroglu E, Hellinger FR, Feng L, Kirmani JF, Lopes DK, Jankowitz BT, Frankel MR, Costalat V, Vora NA, Yoo AJ, Malik AM, Furlan AJ, Rubiera M, Aghaebrahim A, Olivot JM, Tekle WG, Shields R, Graves T, Lewis RJ, Smith WS, Liebeskind DS, Saver JL, Jovin TG Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct N Engl J Med. 2018 01 04;378(1):11-21
Citation Select	Langhorne P, Wu O, Rodgers H, Ashburn A, Bernhardt J A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial Health Technol Assess. 2017 Sep;21(54):1-120
Citation Select	van den Berg LA, Dijkgraaf MG, Berkhemer OA, Fransen PS, Beumer D, Lingsma HF, Majoie CB, Dippel DW, van der Lugt A, van Oostenbrugge RJ, van Zwam WH, Roos YB; MR CLEAN Investigators Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke N Engl J Med. 2017 04 06;376(14):1341-1349
Citation Select	Nielsen Larsen Skjøth Lip Outcomes Associated With Resuming Warfarin Treatment After Hemorrhagic Stroke or Traumatic Intracranial Hemorrhage in Patients With Atrial Fibrillation JAMA Intern Med. 2017 Apr 01;177(4):563-570
Citation Select	AVERT Trial Collaboration group Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial Lancet. 2015 Jul 4;386(9988):46-55. doi: 10.1016/S0140-6736(15)60690-0
Citation Select	Kwok From the Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK. shingkwok@doctors.org.uk., Shoamanesh From the Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK (C.S.K.); Institute of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, Scotland, UK (C.S.K., P.K.M.); Department of Medicine, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada (A.S.); Department of Surgery, Addenbrooke,s Hospital, Cambridge, UK (H.C.C.); Department of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK (Y.K.L.); and Department of Medicine, Brain Research Centre, University of British Columbia, Vancouver Stroke Program, Vancouver, Canada (O.R.B.)., Copley From the Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK (C.S.K.); Institute of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, Scotland, UK (C.S.K., P.K.M.); Department of Medicine, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada (A.S.); Department of Surgery, Addenbrooke,s Hospital, Cambridge, UK (H.C.C.); Department of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK (Y.K.L.); and Department of Medicine, Brain Research Centre, University of British Columbia, Vancouver Stroke Program, Vancouver, Canada (O.R.B.)., Myint From the Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK (C.S.K.); Institute of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, Scotland, UK (C.S.K., P.K.M.); Department of Medicine, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada (A.S.); Department of Surgery, Addenbrooke,s Hospital, Cambridge, UK (H.C.C.); Department of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK (Y.K.L.); and Department of Medicine, Brain Research Centre, University of British Columbia, Vancouver Stroke Program, Vancouver, Canada (O.R.B.)., Loke From the Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK (C.S.K.); Institute of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, Scotland, UK (C.S.K., P.K.M.); Department of Medicine, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada (A.S.); Department of Surgery, Addenbrooke,s Hospital, Cambridge, UK (H.C.C.); Department of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK (Y.K.L.); and Department of Medicine, Brain Research Centre, University of British Columbia, Vancouver Stroke Program, Vancouver, Canada (O.R.B.)., Benavente From the Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK (C.S.K.); Institute of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, Scotland, UK (C.S.K., P.K.M.); Department of Medicine, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada (A.S.); Department of Surgery, Addenbrooke,s Hospital, Cambridge, UK (H.C.C.); Department of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK (Y.K.L.); and Department of Medicine, Brain Research Centre, University of British Columbia, Vancouver Stroke Program, Vancouver, Canada (O.R.B.)., Efficacy of antiplatelet therapy in secondary prevention following lacunar stroke: pooled analysis of randomized trials. Stroke. 2015 Apr;46(4):1014-23
Citation Select	MR CLEAN Investigators; Berkhemer OA, Fransen PS, Beumer D, van den Berg LA, Lingsma HF, Yoo AJ, Schonewille WJ, Vos JA, Nederkoorn PJ, Wermer MJ, van Walderveen MA, Staals J, Hofmeijer J, van Oostayen JA, Lycklama à Nijeholt GJ, Boiten J, Brouwer PA, Emmer BJ, de Bruijn SF, van Dijk LC, Kappelle LJ, Lo RH, van Dijk EJ, de Vries J, de Kort PL, van Rooij WJ, van den Berg JS, van Hasselt BA, Aerden LA, Dallinga RJ, Visser MC, Bot JC, Vroomen PC, Eshghi O, Schreuder TH, Heijboer RJ, Keizer K, Tielbeek AV, den Hertog HM, Gerrits DG, van den Berg-Vos RM, Karas GB, Steyerberg EW, Flach HZ, Marquering HA, Sprengers ME, Jenniskens SF, Beenen LF, van den Berg R, Koudstaal PJ, van Zwam WH, Roos YB, van der Lugt A, van Oostenbrugge RJ, Majoie CB, Dippel DW A randomized trial of intraarterial treatment for acute ischemic stroke N Engl J Med. 2015 Jan 1;372(1):11-20
Citation Select	Bath PM, Krishnan K Interventions for deliberately altering blood pressure in acute stroke Cochrane Database Syst Rev. 2014 Oct 28;2014(10):CD000039. doi: 10.1002/14651858.CD000039.pub3
Citation Select	Jonas DE, Feltner C, Amick HR, Sheridan S, Zheng ZJ, Watford DJ, Carter JL, Rowe CJ, Harris R Screening for Asymptomatic Carotid Artery Stenosis: A Systematic Review and Meta-analysis for the U.S. Preventive Services Task Force Ann Intern Med. 2014 Jul 8. doi: 10.7326/M14-0530. [Epub ahead of print]
Citation Select	CRYSTAL AF Investigators, Sanna T, Diener HC, Passman RS, Di Lazzaro V, Bernstein RA, Morillo CA, Rymer MM, Thijs V, Rogers T, Beckers F, Lindborg K, Brachmann J Cryptogenic stroke and underlying atrial fibrillation N Engl J Med. 2014 Jun 26;370(26):2478-86
Citation Select	EMBRACE Investigators and Coordinators, Gladstone DJ, Spring M, Dorian P, Panzov V, Thorpe KE, Hall J, Vaid H, O,Donnell M, Laupacis A, Côté R, Sharma M, Blakely JA, Shuaib A, Hachinski V, Coutts SB, Sahlas DJ, Teal P, Yip S, Spence JD, Buck B, Verreault S, Casaubon LK, Penn A, Selchen D, Jin A, Howse D, Mehdiratta M, Boyle K, Aviv R, Kapral MK, Mamdani M Atrial fibrillation in patients with cryptogenic stroke N Engl J Med. 2014 Jun 26;370(26):2467-77
Citation Select	Stroke Unit Trialists Collaboration Organised inpatient (stroke unit) care for stroke Cochrane Database Syst Rev. 2013;9:CD000197
Citation Select	the CHANCE Investigators, Wang Y, Wang Y, Zhao X, Liu L, Wang D, Wang C, Wang C, Li H, Meng X, Cui L, Jia J, Dong Q, Xu A, Zeng J, Li Y, Wang Z, Xia H, Johnston SC Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack N Engl J Med. 2013 Jul 4;369(1):11-9
Citation Select	Bonati LH, Lyrer P, Ederle J, Featherstone R, Brown MM, Percutaneous transluminal balloon angioplasty and stenting for carotid artery stenosis. Cochrane Database Syst Rev. 2012;9:CD000515
Citation Select	SPS3 Investigators, Benavente OR, Hart RG, McClure LA, Szychowski JM, Coffey CS, Pearce LA, Effects of clopidogrel added to aspirin in patients with recent lacunar stroke. N Engl J Med. 2012 Aug 30;367(9):817-25
Citation Select	Wardlaw JM, Murray V, Berge E, del Zoppo G, Sandercock P, Lindley RL, Cohen G Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis Lancet. 2012 Jun 23;379(9834):2364-72
Citation Select	IST-3 collaborative group IST-3 collaborative group, Sandercock P, Wardlaw JM, Lindley RI, Dennis M, Cohen G, Murray G, Innes K, Venables G, Czlonkowska A, Kobayashi A, Ricci S, Murray V, Berge E, Slot KB, Hankey GJ, Correia M, Peeters A, Matz K, Lyrer P, Gubitz G, Phillips SJ, Arauz A, The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet. 2012 Jun 23;379(9834):2352-63
Citation Select	Gregson BA, Broderick JP, Auer LM, Batjer H, Chen XC, Juvela S, Morgenstern LB, Pantazis GC, Teernstra OP, Wang WZ, Zuccarello M, Mendelow AD Individual patient data subgroup meta-analysis of surgery for spontaneous supratentorial intracerebral hemorrhage Stroke. 2012 Jun;43(6):1496-504
Citation Select	Salter KL, Foley NC, Zhu L, Jutai JW, Teasell RW Prevention of Poststroke Depression: Does Prophylactic Pharmacotherapy Work? J Stroke Cerebrovasc Dis. 2012 May 1. [Epub ahead of print]
Citation Select	Geeganage CM, Diener HC, Algra A, Chen C, Topol EJ, Dengler R, Markus HS, Bath MW, Bath PM, for the Acute Antiplatelet Stroke Trialists Collaboration for the Acute Antiplatelet Stroke Trialists Collaboration, Dual or Mono Antiplatelet Therapy for Patients With Acute Ischemic Stroke or Transient Ischemic Attack: Systematic Review and Meta-Analysis of Randomized Controlled Trials. Stroke. 2012 Apr;43(4):1058-66. Epub 2012 Jan 26
Citation Select	Cruz-Flores S, Berge E, Whittle IR Surgical decompression for cerebral oedema in acute ischaemic stroke Cochrane Database Syst Rev. 2012;1:CD003435
Citation Select	Murad MH, Shahrour A, Shah ND, Montori VM, Ricotta JJ A systematic review and meta-analysis of randomized trials of carotid endarterectomy vs stenting J Vasc Surg. 2011 Mar;53(3):792-7
Citation Select	Galvin R, Cusack T, O,Grady E, Murphy TB, Stokes E Family-mediated exercise intervention (FAME): evaluation of a novel form of exercise delivery after stroke Stroke. 2011 Mar;42(3):681-6
Citation Select	SCAST Study Group, Sandset EC, Bath PM, Boysen G, Jatuzis D, Kõrv J, Lüders S, Murray GD, Richter PS, Roine RO, Terént A, Thijs V, Berge E The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial Lancet. 2011 Feb 26;377(9767):741-50
Citation Select	Chollet F, Tardy J, Albucher JF, Thalamas C, Berard E, Lamy C, Bejot Y, Deltour S, Jaillard A, Niclot P, Guillon B, Moulin T, Marque P, Pariente J, Arnaud C, Loubinoux I Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial Lancet Neurol. 2011 Feb;10(2):123-30
Citation Select	Ferrarello F, Baccini M, Rinaldi LA, Cavallini MC, Mossello E, Masotti G, Marchionni N, Di Bari M, Efficacy of physiotherapy interventions late after stroke: a meta-analysis. J Neurol Neurosurg Psychiatry. 2011 Feb;82(2):136-43
Citation Select	Cumming TB, Thrift AG, Collier JM, Churilov L, Dewey HM, Donnan GA, Bernhardt J Very early mobilization after stroke fast-tracks return to walking: further results from the phase II AVERT randomized controlled trial Stroke. 2011 Jan;42(1):153-8
Citation Select	Stead LG, Suravaram S, Bellolio MF, Enduri S, Rabinstein A, Gilmore RM, Bhagra A, Manivannan V, Decker WW An assessment of the incremental value of the ABCD2 score in the emergency department evaluation of transient ischemic attack Ann Emerg Med. 2011 Jan;57(1):46-51
Citation Select	Giles MF, Albers GW, Amarenco P, Arsava MM, Asimos A, Ay H, Calvet D, Coutts S, Cucchiara BL, Demchuk AM, Johnston SC, Kelly PJ, Kim AS, Labreuche J, Lavallee PC, Mas JL, Merwick A, Olivot JM, Purroy F, Rosamond WD, Sciolla R, Rothwell PM, Addition of brain infarction to the ABCD2 Score (ABCD2I): a collaborative analysis of unpublished data on 4574 patients. Stroke. 2010 Sep;41(9):1907-13
Citation Select	Marnane M, Duggan CA, Sheehan OC, Merwick A, Hannon N, Curtin D, Harris D, Williams EB, Horgan G, Kyne L, McCormack PM, Duggan J, Moore A, Crispino-O,Connell G, Kelly PJ, Stroke subtype classification to mechanism-specific and undetermined categories by TOAST, A-S-C-O, and causative classification system: direct comparison in the North Dublin population stroke study. Stroke. 2010 Aug;41(8):1579-86
Citation Select	Sheehan OC, Kyne L, Kelly LA, Hannon N, Marnane M, Merwick A, McCormack PM, Duggan J, Moore A, Moroney J, Daly L, Harris D, Horgan G, Williams EB, Kelly PJ Population-based study of ABCD2 score, carotid stenosis, and atrial fibrillation for early stroke prediction after transient ischemic attack: the North Dublin TIA study Stroke. 2010 May;41(5):844-50
Citation Select	Giles MF, Rothwell PM Systematic review and pooled analysis of published and unpublished validations of the ABCD and ABCD2 transient ischemic attack risk scores Stroke. 2010 Apr;41(4):667-73
Citation Select	Harris JE, Eng JJ Strength training improves upper-limb function in individuals with stroke: a meta-analysis Stroke. 2010 Jan;41(1):136-40. Epub 2009 Nov 25
Citation Select	Amarenco P, Labreuche J, Lavallée PC, Meseguer E, Cabrejo L, Slaoui T, Guidoux C, Olivot JM, Abboud H, Lapergue B, Klein IF, Mazighi M, Touboul PJ Does ABCD2 score below 4 allow more time to evaluate patients with a transient ischemic attack? Stroke. 2009 Sep;40(9):3091-5
Citation Select	Feigin VL, Lawes CM, Bennett DA, Barker-Collo SL, Parag V Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review Lancet Neurol. 2009 Apr;8(4):355-69
Citation Select	Potter J, Mistri A, Brodie F, Chernova J, Wilson E, Jagger C, James M, Ford G, Robinson T Controlling hypertension and hypotension immediately post stroke (CHHIPS)--a randomised controlled trial Health Technol Assess. 2009 Jan;13(9):iii, ix-xi, 1-73
Citation Select	Mas JL, Trinquart L, Leys D, Albucher JF, Rousseau H, Viguier A, Bossavy JP, Denis B, Piquet P, Garnier P, Viader F, Touzé E, Julia P, Giroud M, Krause D, Hosseini H, Becquemin JP, Hinzelin G, Houdart E, Hénon H, Neau JP, Bracard S, Onnient Y, Padovani R, Chatellier G, EVA-3S investigators EVA-3S investigators, Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial: results up to 4 years from a randomised, multicentre trial. Lancet Neurol. 2008 Oct;7(10):885-92
Citation Select	Prasad K, Mendelow AD, Gregson B Surgery for primary supratentorial intracerebral haemorrhage Cochrane Database Syst Rev. 2008;(4):CD000200
Citation Select	Halkes PH, Gray LJ, Bath PM, Diener HC, Guiraud-Chaumeil B, Yatsu FM, Algra A Dipyridamole plus aspirin versus aspirin alone in secondary prevention after TIA or stroke: a meta-analysis by risk J Neurol Neurosurg Psychiatry. 2008 Nov;79(11):1218-23
Citation Select	PRoFESS Study Group; Sacco RL, Diener HC, Yusuf S, Cotton D, Ounpuu S, Lawton WA, Palesch Y, Martin RH, Albers GW, Bath P, Bornstein N, Chan BP, Chen ST, Cunha L, Dahlöf B, De Keyser J, Donnan GA, Estol C, Gorelick P, Gu V, Hermansson K, Hilbrich L, Kaste M, Lu C, Machnig T, Pais P, Roberts R, Skvortsova V, Teal P, Toni D, Vandermaelen C, Voigt T, Weber M, Yoon BW Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke N Engl J Med. 2008 Sep 18;359(12):1238-51
Citation Select	PRoFESS Study Group; Yusuf S, Diener HC, Sacco RL, Cotton D, Ounpuu S, Lawton WA, Palesch Y, Martin RH, Albers GW, Bath P, Bornstein N, Chan BP, Chen ST, Cunha L, Dahlöf B, De Keyser J, Donnan GA, Estol C, Gorelick P, Gu V, Hermansson K, Hilbrich L, Kaste M, Lu C, Machnig T, Pais P, Roberts R, Skvortsova V, Teal P, Toni D, VanderMaelen C, Voigt T, Weber M, Yoon BW Telmisartan to prevent recurrent stroke and cardiovascular events N Engl J Med. 2008 Sep 18;359(12):1225-37
Citation Select	ECASS Investigators; Hacke W, Kaste M, Bluhmki E, Brozman M, Dávalos A, Guidetti D, Larrue V, Lees KR, Medeghri Z, Machnig T, Schneider D, von Kummer R, Wahlgren N, Toni D Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke N Engl J Med. 2008 Sep 25;359(13):1317-29
Citation Select	Robinson RG, Jorge RE, Moser DJ, Acion L, Solodkin A, Small SL, Fonzetti P, Hegel M, Arndt S Escitalopram and problem-solving therapy for prevention of poststroke depression: a randomized controlled trial JAMA. 2008 May 28;299(20):2391-400
Citation Select	FAST Trial Investigators; Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, Skolnick BE, Steiner T Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage N Engl J Med. 2008 May 15;358(20):2127-37
Citation Select	Verro P, Gorelick PB, Nguyen D Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: a meta-analysis Stroke. 2008 Apr;39(4):1358-63
Citation Select	Gurm HS, Nallamothu BK, Yadav J Safety of carotid artery stenting for symptomatic carotid artery disease: a meta-analysis Eur Heart J. 2008 Jan;29(1):113-9
Citation Select	Wu CM, McLaughlin K, Lorenzetti DL, Hill MD, Manns BJ, Ghali WA, Early Risk of Stroke After Transient Ischemic Attack: A Systematic Review and Meta-analysis. Arch Intern Med. 2007 Dec 10;167(22):2417-22
Citation Select	Early use of Existing Preventive Strategies for Stroke (EXPRESS) study; Rothwell PM, Giles MF, Chandratheva A, Marquardt L, Geraghty O, Redgrave JN, Lovelock CE, Binney LE, Bull LM, Cuthbertson FC, Welch SJ, Bosch S, Alexander FC, Carasco-Alexander F, Silver LE, Gutnikov SA, Mehta Z Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison Lancet. 2007 Oct 20;370(9596):1432-42
Citation Select	Liao J, Khalid Z, Scallan C, Morillo C, O,Donnell M Noninvasive cardiac monitoring for detecting paroxysmal atrial fibrillation or flutter after acute ischemic stroke: a systematic review Stroke. 2007 Nov;38(11):2935-40
Citation Select	DECIMAL Investigators; Vahedi K, Vicaut E, Mateo J, Kurtz A, Orabi M, Guichard JP, Boutron C, Couvreur G, Rouanet F, Touzé E, Guillon B, Carpentier A, Yelnik A, George B, Payen D, Bousser MG Sequential-design, multicenter, randomized, controlled trial of early decompressive craniectomy in malignant middle cerebral artery infarction (DECIMAL Trial). Stroke. 2007 Sep;38(9):2506-17
Citation Select	DESTINY Study Group; Jüttler E, Schwab S, Schmiedek P, Unterberg A, Hennerici M, Woitzik J, Witte S, Jenetzky E, Hacke W Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery (DESTINY): a randomized, controlled trial Stroke. 2007 Sep;38(9):2518-25
Citation Select	Johnston SC, Rothwell PM, Nguyen-Huynh MN, Giles MF, Elkins JS, Bernstein AL, Sidney S, Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet. 2007 Jan 27;369(9558):283-92
Citation Select	Chalela JA, Kidwell CS, Nentwich LM, Luby M, Butman JA, Demchuk AM, Hill MD, Patronas N, Latour L, Warach S, Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison. Lancet. 2007 Jan 27;369(9558):293-8
Citation Select	Paciaroni M, Agnelli G, Micheli S, Caso V Efficacy and safety of anticoagulant treatment in acute cardioembolic stroke: a meta-analysis of randomized controlled trials Stroke. 2007 Feb;38(2):423-30
Citation Select	Tsivgoulis G, Spengos K, Manta P, Karandreas N, Zambelis T, Zakopoulos N, Vassilopoulos D, Validation of the ABCD score in identifying individuals at high early riskof stroke after a transient ischemic attack: a hospital-based case series study. Stroke. 2006 Dec;37(12):2892-7
Citation Select	Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators; Amarenco P, Bogousslavsky J, Callahan A 3rd, Goldstein LB, Hennerici M, Rudolph AE, Sillesen H, Simunovic L, Szarek M, Welch KM, Zivin JA High-dose atorvastatin after stroke or transient ischemic attack N Engl J Med. 2006 Aug 10;355(6):549-59
Citation Select	Chambers B, Donnan G, Chambers B Carotid endarterectomy for asymptomatic carotid stenosis Cochrane Database Syst Rev. 2005 Oct 19;(4):CD001923
Citation Select	Rothwell PM, Giles MF, Flossmann E, Lovelock CE, Redgrave JN, Warlow CP, Mehta Z A simple score (ABCD) to identify individuals at high early risk of stroke after transient ischaemic attack Lancet. 2005 Jul 2;366(9479):29-36
Citation Select	Aguilar M, Hart R Oral anticoagulants for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks Cochrane Database Syst Rev. 2005 Jul 20;(3):CD001927
Citation Select	MOSES Study Group; Schrader J, Luders S, Kulschewski A, Hammersen F, Plate K, Berger J, Zidek W, Dominiak P, Diener HC Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES) Stroke. 2005 Jun;36(6):1218-26. Epub 2005 May 5
Citation Select	Goldstein LB, Simel DL Is this patient having a stroke? JAMA. 2005 May 18;293(19):2391-402
Citation Select	Warfarin-Aspirin Symptomatic Intracranial Disease Trial Investigators; Chimowitz MI, Lynn MJ, Howlett-Smith H, Stern BJ, Hertzberg VS, Frankel MR, Levine SR, Chaturvedi S, Kasner SE, Benesch CG, Sila CA, Jovin TG, Romano JG Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis N Engl J Med. 2005 Mar 31;352(13):1305-16
Citation Select	FOOD Trial Collaboration; Dennis MS, Lewis SC, Warlow C Effect of timing and method of enteral tube feeding for dysphagic stroke patients (FOOD): a multicentre randomised controlled trial Lancet. 2005 Feb 26;365(9461):764-72
Citation Select	Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators; Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, Skolnick BE, Steiner T Recombinant activated factor VII for acute intracerebral hemorrhage N Engl J Med. 2005 Feb 24;352(8):777-85
Citation Select	Briel M, Studer M, Glass TR, Bucher HC Effects of statins on stroke prevention in patients with and without coronary heart disease: a meta-analysis of randomized controlled trials Am J Med. 2004 Oct 15;117(8):596-606
Citation Select	Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy Investigators; Yadav JS, Wholey MH, Kuntz RE, Fayad P, Katzen BT, Mishkel GJ, Bajwa TK, Whitlow P, Strickman NE, Jaff MR, Popma JJ, Snead DB, Cutlip DE, Firth BG, Ouriel K Protected carotid-artery stenting versus endarterectomy in high-risk patients N Engl J Med. 2004 Oct 7;351(15):1493-501
Citation Select	Gubitz G, Sandercock P, Counsell C Anticoagulants for acute ischaemic stroke Cochrane Database Syst Rev. 2004;(3):CD000024
Citation Select	Diener HC, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M, Leys D, Matias-Guiu J, Rupprecht HJ; MATCH investigators Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial Lancet. 2004 Jul 24;364(9431):331-7
Citation Select	Halliday A, Mansfield A, Marro J, Peto C, Peto R, Potter J, Thomas D; MRC Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial Lancet. 2004 May 8;363(9420):1491-502
Citation Select	Collins R, Armitage J, Parish S, Sleight P, Peto R; Heart Protection Study Collaborative Group Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions Lancet. 2004 Mar 6;363(9411):757-67
Citation Select	Acute Candesartan Cilexetil Therapy in Stroke Survivors Study Group; Schrader J, Luders S, Kulschewski A, Berger J, Zidek W, Treib J, Einhaupl K, Diener HC, Dominiak P The ACCESS Study: evaluation of Acute Candesartan Cilexetil Therapy in Stroke Survivors Stroke. 2003 Jul;34(7):1699-703
Citation Select	van Walraven C, Hart RG, Singer DE, Laupacis A, Connolly S, Petersen P, Koudstaal PJ, Chang Y, Hellemons B Oral anticoagulants vs aspirin in nonvalvular atrial fibrillation: an individual patient meta-analysis JAMA. 2002 Nov 20;288(19):2441-8
Citation Select	Kolominsky-Rabas PL, Weber M, Gefeller O, Neundoerfer B, Heuschmann PU, Epidemiology of ischemic stroke subtypes according to TOAST criteria: incidence, recurrence, and long-term survival in ischemic stroke subtypes: a population-based study. Stroke. 2001 Dec 1;32(12):2735-40
Citation Select	PROGRESS Collaborative Group Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack Lancet. 2001 Sep 29;358(9287):1033-41
Citation Select	CAST and IST collaborative groups; Chen ZM, Sandercock P, Pan HC, Counsell C, Collins R, Liu LS, Xie JX, Warlow C, Peto R Indications for early aspirin use in acute ischemic stroke : A combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial Stroke. 2000 Jun;31(6):1240-9
Citation Select	Berge E, Abdelnoor M, Nakstad PH, Sandset PM Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: a double-blind randomised study. HAEST Study Group. Heparin in Acute Embolic Stroke Trial Lancet. 2000 Apr 8;355(9211):1205-10
Citation Select	North American Symptomatic Carotid Endarterectomy Trial Group; Inzitari D, Eliasziw M, Sharpe BL, Fox AJ, Barnett HJ Risk factors and outcome of patients with carotid artery stenosis presenting with lacunar stroke Neurology. 2000 Feb 8;54(3):660-6
Citation Select	Johnson ES, Lanes SF, Wentworth CE 3d, et al A metaregression analysis of the dose-response effect of aspirin on stroke Arch Intern Med. 1999 Jun 14;159:1248-53
Citation Select	Benavente O, Moher D, Pham B Carotid endarterectomy for asymptomatic carotid stenosis: a meta-analysis BMJ. 1998 Nov 28;317(7171):1477-1480
Citation Select	CAST (Chinese Acute Stroke Trial) Collaborative Group CAST: randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke Lancet. 1997 Jun 7;349(9066):1641-1649
Citation Select	International Stroke Trial Collaborative Group The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke Lancet. 1997 May 31;349(9065):1569-1581
Citation Select	Kay R, Wong KS, Yu YL, Chan YW, Tsoi TH, Ahuja AT, Chan FL, Fong KY, Law CB, Wong A Low-molecular-weight heparin for the treatment of acute ischemic stroke. N Engl J Med. 1995 Dec 14;333(24):1588-1593
Citation Select	No authors listed Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation: Stroke Prevention in Atrial Fibrillation II Study Lancet. 1994 Mar 19;343(8899):687-91
Citation Select	The Dutch TIA Trial Study Group A comparison of two doses of aspirin (30 mg vs 283 mg a day) in patients after a transient ischemic attack or minor ischemic stroke N Engl J Med. 1991 Oct 31;325(18):1261-6
Citation Select	Duke RJ, Bloch RF, Turpie AG, Trebilcock R, Bayer N Intravenous heparin for the prevention of stroke progression in acute partial stable stroke Ann Intern Med. 1986 Dec;105(6):825-828