Citation Select	Annane D, Briegel J, Granton D, Bellissant E, Bollaert PE, Keh D, Kupfer Y, Pirracchio R, Rochwerg B Corticosteroids for treating sepsis in children and adults Cochrane Database Syst Rev. 2025 Jun 5;6(6):CD002243. doi: 10.1002/14651858.CD002243.pub5
Citation Select	Ahn C, Yu G, Shin TG, Cho Y, Park S, Suh GY Comparison of Early and Late Norepinephrine Administration in Patients With Septic Shock: A Systematic Review and Meta-analysis Chest. 2024 Jul 5:S0012-3692(24)04581-1. doi: 10.1016/j.chest.2024.05.042
Citation Select	Zhao Y, Zang B, Wang Q Prolonged versus intermittent β-lactam infusion in sepsis: a systematic review and meta-analysis of randomized controlled trials Ann Intensive Care. 2024 Feb 18;14(1):30. doi: 10.1186/s13613-024-01263-9
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Citation Select	Heilmann E, Gregoriano C, Annane D, Reinhart K, Bouadma L, Wolff M, Chastre J, Luyt CE, Tubach F, Branche AR, Briel M, Christ-Crain M, Welte T, Corti C, de Jong E, Nijsten M, de Lange DW, van Oers JAH, Beishuizen A, Girbes ARJ, Deliberato RO, Schroeder S, Kristoffersen KB, Layios N, Damas P, Lima SSS, Nobre V, Wei L, Oliveira CF, Shehabi Y, Stolz D, Tamm M, Verduri A, Wang JX, Drevet S, Gavazzi G, Mueller B, Schuetz P Duration of antibiotic treatment using procalcitonin-guided treatment algorithms in older patients: a patient-level meta-analysis from randomized controlled trials Age Ageing. 2021 Sep 11;50(5):1546-1556. doi: 10.1093/ageing/afab078
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Citation Select	CRICS-TRIGGERSEP Network; Annane D, Renault A, Brun-Buisson C, Megarbane B, Quenot JP, Siami S, Cariou A, Forceville X, Schwebel C, Martin C, Timsit JF, Misset B, Ali Benali M, Colin G, Souweine B, Asehnoune K, Mercier E, Chimot L, Charpentier C, François B, Boulain T, Petitpas F, Constantin JM, Dhonneur G, Baudin F, Combes A, Bohé J, Loriferne JF, Amathieu R, Cook F, Slama M, Leroy O, Capellier G, Dargent A, Hissem T, Maxime V, Bellissant E Hydrocortisone plus Fludrocortisone for Adults with Septic Shock N Engl J Med. 2018 Mar 1;378(9):809-818
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Citation Select	PRISM Investigators Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis N Engl J Med. 2017 Jun 08;376(23):2223-2234
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Citation Select	The ProCESS Investigators The ProCESS Investigators, A Randomized Trial of Protocol-Based Care for Early Septic Shock. N Engl J Med. 2014 May 1;370(18):1683-93
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Citation Select	Annane D, Bellissant E, Bollaert PE, Briegel J, Confalonieri M, De Gaudio R, Keh D, Kupfer Y, Oppert M, Meduri GU Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review JAMA. 2009 Jun 10;301(22):2362-75
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Citation Select	Brunkhorst FM, Engel C, Bloos F, Meier-Hellmann A, Ragaller M, Weiler N, Moerer O, Gruendling M, Oppert M, Grond S, Olthoff D, Jaschinski U, John S, Rossaint R, Welte T, Schaefer M, Kern P, Kuhnt E, Kiehntopf M, Hartog C, Natanson C, Loeffler M, Reinhart K, German Competence Network Sepsis (SepNet) Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med. 2008 Jan 10;358(2):125-39
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