working cost-effectiveness study: data sources: studies included as data source / Meta-analysis: Rhythm control versus rate control
DISEASE INTERVENTION COMPARISON RESULTS
Arch Intern Med. 2005 Feb 14;165(3):258-62 Meta-Analysis
IN StudyID: Denus 2005, atrial fibrillation, rate control strategy The Use of
rate control strategy (drugs and anticoagulation)
As Treatment, Chronic
Is equal Than
rhythm control strategy (cardioversion and antiarrhythmics)
To reduce all-cause mortality: 14.6% rhythm-control vs 13.0% rate-control. A trend existed in favour of rate-control: OR 0.87; 95%CI 0.74-1.02
Eur Heart J. 2005 Oct;26(19):2000-6. Epub 2005 May 4 Meta-Analysis
IN StudyID: Testa 2005, atrial fibrillation, rate control strategy The Use of
rate control strategy
As Treatment, Chronic
Is better Than
rhythm control strategy
To reduce a combined endpoint of all cause death and thromboembolic stroke (OR 0.84 (0.73, 0.98)). No difference in all-cause death, systemic embolism and major bleeding.