Drugs for rate control
DISEASE INTERVENTION COMPARISON RESULTS
J Fam Pract. 2000 Jan;49(1):47-59 Systematic Review
IN atrial fibrillation The Use of
calcium-channel blockers verapamil or diltiazem, beta-blockers, digoxin
As Treatment, Chronic
Is better Than
placebo
To adequately control heart rate. Verapamil, diltiazem and beta-blockers controlled better heart rate during exercise than digoxine.
J Am Coll Cardiol. 2004 Apr 7;43(7):1201-8 Randomized Controlled Trial
IN atrial fibrillation, persistent The Use of
beta-blockers, but with frequent changes and combination needed
As Treatment, Chronic
Is better Than
calcium-channel blockers, diltiazem, digoxin
To adequately control heart rate: 70% beta-blockers, 54% calcium-channel blockers, 58% digoxin.
Crit Care Med. 2009 Jul;37(7):2174-9 Randomized Controlled Trial
IN atrial fibrillation, recent onset, acute, symptomatic The Use of
diltiazem, intravenous
As Treatment, Acute
Is better Than
digoxin, amiodarone, intravenous
To adequately control heart rate at 24 hours (90% diltiazem, 74% digoxine or amiodarone)