prophylaxis using antiarrhythmics, amiodarone, 600 mg oral single dose per day from Day-1 to Day7 plus IV perfusion during surgery
DISEASE INTERVENTION COMPARISON RESULTS
Eur Heart J. 2006 Jul;27(13):1584-91. Epub 2006 Jun 7 Randomized Controlled Trial
IN atrial fibrillation, postoperative, cardiac surgery The Use of
prophylaxis using antiarrhythmics, amiodarone, 600 mg oral single dose per day from Day-1 to Day7 plus IV perfusion during surgery
As Prevention, Primary
Is better Than
placebo
To reduce the incidence of post-operative AF: 34% with amiodarone VS 85% placebo. Also reduced hospitalization length of stay. Blood concentrations of amiodarone sig. differed between patients.