apixaban, oral factor Xa inhibitors
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2011 Feb 10. [Epub ahead of print] Randomized Controlled Trial, Multicenter Study
IN atrial fibrillation, non valvular, stroke, ischemic, cerebral infarction, embolic, patients not suitable for vitamine K antagonists, warfarin The Use of
apixaban, oral factor Xa inhibitors
As Treatment, Chronic
Is better Than
aspirin
To reduce stroke or systemic embolism (1.6% per year apixaban VS 3.7% aspirin) while not increasing major bleeding (1.4% per year apixaban VS 1.2% aspirin)