amiodarone, low dose maintenace
DISEASE INTERVENTION COMPARISON RESULTS
J Am Coll Cardiol. 1997 Sep;30(3):791-8 Meta-Analysis
IN StudyID: Vorperian 1997, antiarrhythmic drugs, amiodarone, adverse effects The Use of
amiodarone, low dose maintenace
As Treatment, Chronic
Is worse Than
placebo
To produce at 12 months more side effects: thyroid OR 4,2 ; thyroid OR 4,2 ; ocular OR 3,4 ; skin OR 2,5 ; bradycardic OR 2,2 ; neurologic OR 2,0. Treatment withdrawal: 23% in amiodarone, 15% placebo