atrial fibrillation, persistent, rate control, pharmacologic, Study ID: PALLAS 2011
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2011 Dec 15;365(24):2268-76 Randomized Controlled Trial, Multicenter Study
IN atrial fibrillation, persistent, rate control, pharmacologic, Study ID: PALLAS 2011 The Use of
dronedarone
As Treatment, Chronic
Is worse Than
placebo
To modify cardiovascular events: dronedarone increased deaths from cardiovascular causes (HR 2.1), stroke (HR 2.3) and heart failure (HR 1.8)