atrial fibrillation, non-pharmacological treatment
DISEASE INTERVENTION COMPARISON RESULTS
Arch Intern Med. 2008 Mar 24;168(6):581-6 Systematic Review
IN atrial fibrillation, non-pharmacological treatment The Use of
catheter ablation, radiofrequency
As Treatment, Chronic
Is better Than
long-term antiarrhythmic drug therapy
To reduce at 1 year recurrence of AF (24.% abalation VS 81.2% antiarrhythmics) and reduce adverse events. No other clinical outcome assessed (mortality? heart failure?)
J Am Coll Cardiol. 2006 Jun 20;47(12):2513-20 Cost-Effectiveness
IN atrial fibrillation, non-pharmacological treatment The Use of
catheter ablation, radiofrequency
As Treatment, Chronic
Is better Than
other treatment strategies
To increase QALY at acceptable costs: ablation can be cost-effective in patients with moderate to high risk of stroke, but not at low risk.
Ann Intern Med. 2009 Aug 4;151(3):191-202. Epub 2009 Jul 6. Systematic Review
IN atrial fibrillation, non-pharmacological treatment The Use of
catheter ablation, radiofrequency, circumferential pulmonary vein ablation
As Treatment, Chronic
Is better Than
long-term antiarrhythmic drug therapy
To maintain sinus rhythm and possibly (lower strenght of evidence) improve quality of life, promote avoidance of anticoagulation, and decrease hospitalisation.