atrial fibrillation, embolic complications
DISEASE INTERVENTION COMPARISON RESULTS
Lancet. 2000 Mar 18;355(9208):956-62 Decision Model
IN atrial fibrillation, embolic complications The Use of
vitamin K antagonists, warfarin
As Treatment, Chronic
Is better Than
aspirin or placebo
To reduce stroke and parterial embolism for most patients, specially those older
Heart. 2008 Dec;94(12):1607-13 Meta-Analysis
IN atrial fibrillation, embolic complications, systemic non-cerebral embolism The Use of
vitamin K antagonists, warfarin
As Treatment, Chronic
Is better Than
placebo or antiplatelet agents, aspirin
To reduce systemic embolism: OR 0.5 VS aspirin, OR 0.7 VS placebo. Increased major bleeding: OR 3 VS placebo.