atrial fibrillation, elderly patients
DISEASE INTERVENTION COMPARISON RESULTS
Arch Intern Med. 1999 Apr 12;159(7):677-85 Decision Model
IN atrial fibrillation, elderly patients The Use of
warfarin
As Treatment, Chronic
Is better Than
aspirin or no treatment
To increase, in patients with average risk of stroke, expected QALYs: 12.9 warfarin, 11.2 aspirin and 10.15 no Tt.
J Am Geriatr Soc. 2002 May;50(5):863-9 Decision Model
IN atrial fibrillation, elderly patients The Use of
warfarin, anticoagulants
As Treatment, Chronic
Is equal Than
aspirin or no treatment
To increase expected QALYs: no compelling evidence of gain in quality-adjusted life expectancy with anticoagulation.
Lancet. 2007 Aug 11;370(9586):493-503 Randomized Controlled Trial, Multicenter Study
IN atrial fibrillation, elderly patients, not high haemorrahgic risk, noT high stroke risk, anticoagulants, vitamin K antagonists, bleeding risk, elder patients The Use of
vitamin K antagonists, warfarin
As Treatment, Chronic
Is better Than
aspirin
To reduce all-type strokes: 1.8% warfarin versus 3.8% aspirin. No increase at all in major haemorrhages.