antiarrthythmic drugs, amiodarone, adverse effects, thyroid
DISEASE INTERVENTION COMPARISON RESULTS
S Afr Med J. 2005 Mar;95(3):180-3 Cohorts
IN antiarrthythmic drugs, amiodarone, adverse effects, thyroid The Use of
amiodarone
As Treatment, Chronic
Is bad Than
no treatment
To develop thyroid dysfunction (either hyper or hypothyroidism): 27.6% of treated patients after a mean of 943 days of treatment VS mean 547 days in euthyroid patients.
Am J Med. 2007 Oct;120(10):880-5 Randomized Controlled Trial
IN antiarrthythmic drugs, amiodarone, adverse effects, thyroid The Use of
amiodarone
As Treatment, Chronic
Is worse Than
placebo
To alter thyroid function: hypothyroidism developed in 30.8%, hyperthyroidism in 5.3%