StudyID: AFFIRM Substudy 2003, atrial fibrillation, persistent
DISEASE INTERVENTION COMPARISON RESULTS
J Am Coll Cardiol. 2003 Jul 2;42(1):20-9 Randomized Controlled Trial
IN StudyID: AFFIRM Substudy 2003, atrial fibrillation, persistent The Use of
amiodarone
As Treatment, Chronic
Is better Than
sotalol, or a class I drug
To composite outcome (patients alive, in sinus rhythm, with no additional cardioversions and still taking the assigned drug) at 12 months: 60% amiodarone, 38% sotalol, 23% class I agents. Adverse effects were common.