Stroke, ischemic, massive : Surgical decompression for cerebral oedema
DISEASE INTERVENTION COMPARISON RESULTS
Stroke. 2007 Sep;38(9):2518-25 Randomized Controlled Trial
IN stroke, ischemic, cerebral infarction, massive, life-threatening The Use of
decompressive surgery by hemicraniectomy
As Treatment, Acute
Is better Than
conservative medical care
To reduce mortality at 30 days (12% hemicraniectomy VS 53% conservative care) and probably improve proportion of patients with better status functional status at 12 monts (47% surgery VS 27% conservative, p=0.23)
Stroke. 2007 Sep;38(9):2506-17 Randomized Controlled Trial, Multicenter Study
IN stroke, ischemic, cerebral infarction, massive, life-threatening The Use of
surgery, decompressive craniectomy
As Treatment, Acute
Is better Than
conservative medical care
To reduce death (52% absolute reduction) and probably improve proportion of patients with better status functional status at 12 monts (50% surgery VS 22% conservative, p=0.10)
Cochrane Database Syst Rev. 2012;1:CD003435 Systematic Review, Cochrane Review
IN stroke, ischemic, cerebral infarction, massive, life-threatening, 60 years of age or younger The Use of
surgery, decompressive craniectomy
As Treatment, Acute
Is better Than
conservative medical care
To reduced the risk of death at the end of follow-up (OR 0.19) and the risk of death or severe disability (Rankin > 4) at 12 months (OR 0.26)