Renal failure, in elderly patients: creatinine based equations for estimating the glomerular filtration rate | ||||
DISEASE | INTERVENTION | COMPARISON | RESULTS | |
J Am Geriatr Soc. 2009 Sep;57(9):1638-43 | Diagnostic | |||
IN kidney disease, chronic, glomerular filtration estimation, elderly patients |
The Use of
Cockcroft-Gault equation As Diagnostic Tool |
Is better Than
Modification of Diet in Renal Disease (MDRD) equation |
To estimate measured 24-hour creatinine clearance (CrCl): Cockcroft slightly underestimates CrCl, and MDRD strongly overestimates it. | |
J Nephrol. 2010 May-Jun;23(3):306-13 | Diagnostic | |||
IN kidney disease, chronic, glomerular filtration estimation, elderly patients |
The Use of
measured 24-hour creatinine clearance, Modification of Diet in Renal Disease (MDRD) equation, Mayo Clinic quadratic equation As Diagnostic Tool |
Is bad Than
no gold standard comparison done |
To accurately estimate glomerular filtration rate: values derived by MDRD and MCQ equations and CrCl significantly differed from each other in patients > 85 years. | |
Age Ageing. 2010 Sep;39(5):542-8 | Systematic Review | |||
IN kidney disease, chronic, glomerular filtration estimation, elderly patients |
The Use of
Modification of Diet in Renal Disease (MDRD) equation As Diagnostic Tool |
Is equal Than
Cockcroft-Gault equation, serum cystatin C |
To accurately estimate (measured by a standard) glomerular fiiltration rate. All 3 methods better than serum creatinine alone, or than other equations. | |
J Am Geriatr Soc. 2003 Jul;51(7):1012-7 | Diagnostic | |||
IN kidney disease, chronic, glomerular filtration estimation, elderly patients |
The Use of
Modification of Diet in Renal Disease (MDRD) equation As Diagnostic Tool |
Is equal Than
Cockcroft-Gault or Baracskay equations |
To accurately estimate (51Cromium-EDTA measured) glomerular filtration rate. MDRD was more accurate but Cockcroft was more precise and overall performance was similar for both | |
Nephron Clin Pract. 2005;101(1):c1-8 | Diagnostic | |||
IN kidney disease, chronic, glomerular filtration estimation, elderly patients |
The Use of
Modification of Diet in Renal Disease (MDRD) equation As Diagnostic Tool |
Is better Than
Cockcroft-Gault or Baracskay equations |
To accurately estimated (inulin measured) glomerular filtration rate. All equation had low accuracy and precision and underestimated actual FGR, the MDRD the less. All did better, however, than using serum creatinine alone. |