Renal artery stenosis (atherosclerotic): Revascularizacion versus medical therapy alone
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2009 Nov 12;361(20):1953-62 Randomized Controlled Trial, Multicenter Study
IN hypertension, secondary, kidney disease, chronic, renal artery stenosis, atherosclerotic The Use of
renal artery revascularization
As Treatment, Chronic
Is equal Than
medical therapy alone
To modify significantly progression of renal failure, blood pressure, renal events, major cardiovascular events or death. There were aprox 5% of serious complications in the revascularization group.
N Engl J Med. 2014 Jan 2;370(1):13-22 Randomized Controlled Trial, Multicenter Study
IN hypertension, secondary, kidney disease, chronic, renal artery stenosis, atherosclerotic, older patients The Use of
renal artery revascularization, stenting
As Treatment, Chronic
Is equal Than
medical therapy alone
To modify at 3.5 years death or cardivascular or renal events (myocardial infarction, stroke, heart failure, progressive renal insufficiency, renal-replacement therapy): 35% both treatments. Systolic blood pressure were lower in stenting group
Ann Intern Med. 2006 Dec 19;145(12):901-12. Epub 2006 Oct 24 Systematic Review
IN hypertension, secondary, renal artery stenosis, atherosclerotic The Use of
renal artery revascularization, angioplasty
As Treatment, Chronic
Is equal Than
aggressive medical therapy
To improve mortality, cardiovascular events, or renal failure, but the evidence found was weak and no study directly compared revascularization with medical Tt.