Coronary disease: Glucose-insulin-potassium therapy for ST-segment elevated myocardial infarction
DISEASE INTERVENTION COMPARISON RESULTS
JAMA. 2007 Nov 28;298(20):2399-405 Randomized Controlled Trial, Multicenter Study
IN coronary disease, myocardial infarction, ST-segment elevation The Use of
glucose-insulin-potassium infusion
As Treatment, Acute
Is equal Than
no this treatment
To improve death or heart failure: 6.2% in the GIK group VS 5.5% in the control group, p non significant.
Am J Cardiol. 2005 Oct 15;96(8):1053-8. Epub 2005 Aug 24 Randomized Controlled Trial
IN coronary disease, myocardial infarction, ST-segment elevation The Use of
glucose-insulin-potassium infusion
As Treatment, Acute
Is better Than
usual care (thrombolysis with streptokinase) alone
To reduce at 1 month major adverse cardiac events (death, reinfarction, serious arrhythmias and severe heart failure): 10% with gluc-insulin-K vs 32.5% without.
JAMA. 2005 Jan 26;293(4):437-46 Randomized Controlled Trial, Multicenter Study
IN coronary disease, myocardial infarction, ST-segment elevation The Use of
glucose-insulin-potassium infusion
As Treatment, Acute
Is equal Than
usual care alone
To reduce mortality, cardiogenic shock or reinfarction at 30 days