Atrial fibrillation: Circumferential pulmonary-vein catheter ablation for treatment
DISEASE INTERVENTION COMPARISON RESULTS
Arch Intern Med. 2008 Mar 24;168(6):581-6 Systematic Review
IN atrial fibrillation, non-pharmacological treatment The Use of
catheter ablation, radiofrequency
As Treatment, Acute
Is better Than
cardioversion and chronic antiarrhythmic drugs
To reduce at 1 year recurrence of AF (24.% abalation VS 81.2% antiarrhythmics) and reduce adverse events. No other clinical outcome assessed (mortality? heart failure?)
Circ Arrhythm Electrophysiol. 2014 Oct;7(5):853-60 Systematic Review
IN atrial fibrillation, non-pharmacological treatment, selected patients The Use of
catheter ablation
As Treatment, Acute
Is better Than
cardioversion and chronic antiarrhythmic drugs
To recurrence of AF (28% ablation VS 65% antiarrhythmics), either as firts-line or second-line therapy
JAMA. 2005 Jun 1;293(21):2634-40 Randomized Controlled Trial, Multicenter Study
IN atrial fibrillation, paroxysmal, non-pharmacological treatment The Use of
catheter ablation, radiofrequency
As Treatment, Acute
Is better Than
chronic antiarrhythmic drug therapy
To reduce symptomatic AF recurrence (13% with ablation VS 63% with drugs) and hospitalizations (9% VS 54%). Pulmonary vein stenosis in 6% patients with ablation.
J Am Coll Cardiol. 2006 Dec 5;48(11):2340-7 Randomized Controlled Trial
IN atrial fibrillation, paroxysmal, refractory, non-pharmacological treatment The Use of
catheter ablation, circumferential pulmonary vein ablation
As Treatment, Chronic
Is better Than
change to another antiarrhythmic drug
To reduce, at 1 year, recurrences of AF: 7% with ablation VS 65% with drugs. Ablation was repeated in 9% patients and 2 severe adverse effects.
N Engl J Med. 2006 Mar 2;354(9):934-41 Randomized Controlled Trial
IN atrial fibrillation, persistent, non-pharmacological treatment The Use of
catheter ablation, radiofrequency
As Treatment, Acute
Is better Than
cardioversion and chronic amiodarone
To reduce atrial fibrillation recurrence: 26% with ablation VS 42% amiodarone; and improve symptoms. Complications: atypical atrial flutter.
Eur Heart J. 2006 Jan;27(2):216-21. Epub 2005 Oct 7 Randomized Controlled Trial
IN atrial fibrillation, refractory, non-pharmacological treatment The Use of
catheter ablation, radiofrequency AND and antiarrhythmic drugs (various)
As Treatment, Chronic
Is better Than
antiarrhythmic drug therapy alone (various drugs)
To prevent AF recurrence: 44% with ablation VS 91% without. Three (4.4%) major complications were related to ablation: stroke, pericardial effusion and a phrenic paralysis.