Atrial fibrillation and Heart failure: Circumferential pulmonary-vein catheter ablation for treatment
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2004 Dec 2;351(23):2373-83 Clinical Trial (non-controlled, non-randomized)
IN atrial fibrillation, heart failure, non-pharmacological treatment The Use of
catheter ablation, radiofrequency
As Treatment, Acute
Is good Than
no comparison group in this trial
To restore and maintain sinus rhythm: after 12 months 70% of patients maintained SR. Improve ejection fraction in those patients with heart failure (average of plus 20% at 12 months)
N Engl J Med. 2018 02 01;378(5):417-427 Randomized Controlled Trial, Multicenter Study
IN atrial fibrillation, heart failure, reduced ejection fraction, non-pharmacological treatment The Use of
catheter ablation
As Treatment, Acute
Is better Than
medical-therapy only
To reduce mortality from any cause (13%] ablation VS 25%), hospitalization for worsening heart failure (21% ablation VS 36%) or death from cardiovascular causes (11% ablation VS 22%)