bisphosphonates, regularly administered at high dose IV
DISEASE INTERVENTION COMPARISON RESULTS
Health Technol Assess. 2004;8(4):1-176 Systematic Review
IN cancer, bone metastases The Use of
bisphosphonates, regularly administered at high dose IV
As Treatment, Acute, Chronic
Is better Than
placebo
To control hypercalcemia (pamidronate better than clodronate or etidronate) and prevent skeletal related events (fractures, pain) Possible effect to prevent developping bone metastases in breast cancer