beta-lactam monotherapy, as intitial empiric antibiotic
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2015 Apr 2;372(14):1312-23 Randomized Controlled Trial, Multicenter Study
IN pneumonia, community-adquired, hospitalized patients, old patients The Use of
beta-lactam monotherapy, as intitial empiric antibiotic
As Treatment, Acute
Is better Than
beta-lactam + macrolide combination, and equal as fluoroquinolone
To reduce mortality at 90 days: 9.0% with beta-lactam monotherapy, 11.1% beta-lactam-macrolide combination, and 8.8% fluoroquinolone monotherapy.