azithromycin (single 1-g dose of two 500-mg tablets)
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2006 Jun 8;354(23):2452-62 Randomized Controlled Trial
IN cholera The Use of
azithromycin (single 1-g dose of two 500-mg tablets)
As Treatment, Acute
Is better Than
ciprofloxacin (also a single 1-g dose of two 500-mg tablets)
To produce clinical success (stop watery stools within 48 hours after administration): 73% with azytro VS 27% with cipro. The lack of efficacy of ciprofloxacin may result from its diminished activity against strains in Bangladesh.