anticoagulants, oral factor Xa inhibitors, rivaroxaban, 20 mg once daily
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2011 Sep 8;365(10):883-91. Epub 2011 Aug 10 Randomized Controlled Trial, Multicenter Study
IN atrial fibrillation The Use of
anticoagulants, oral factor Xa inhibitors, rivaroxaban, 20 mg once daily
As Treatment, Chronic
Is equal Than
dose-adjusted warfarin
To reduce stroke or systemic embolism (2.1% per year rivaroxaban VS 2.4% warfarin), or cause clinically relevant bleeding, major or nonmajor (15% per year both)