antibiotics: cefotaxime and metronidazole IV first, then ciprofloxacine and metronidazole PO
DISEASE INTERVENTION COMPARISON RESULTS
Br J Surg. 2009 May;96(5):473-81 Randomized Controlled Trial, Multicenter Study
IN pain, abdominal, acute, appendicitis, adults The Use of
antibiotics: cefotaxime and metronidazole IV first, then ciprofloxacine and metronidazole PO
As Treatment, Acute
Is better Than
appendicectomy, open or laparoscopy
To reduce major complications: 5.4% antibiotics VS 10.8% surgery by intention to treat, 2% antibiotics VS 10% surgery per protocol. 7% of patients on antibiotics need acute surgery, and 9% had recurrence at 1 year.