angiotensin converting enzyme inhibitors (ACEI), perindopril
DISEASE INTERVENTION COMPARISON RESULTS
Eur Heart J. 2006 Oct;27(19):2338-45 Randomized Controlled Trial, Multicenter Study
IN heart failure, chronic, diastolic (preserved ejection fraction), elder patients The Use of
angiotensin converting enzyme inhibitors (ACEI), perindopril
As Treatment, Chronic
Is better Than
placebo
To reduce at 1 year hospitalizations for heart failure (HR 0.63) and improve functional class. However, differences in primary combined outcome at 2 years were not significant
N Engl J Med. 2008 May 1;358(18):1887-98 Randomized Controlled Trial, Multicenter Study
IN hypertension, primary, elder patients The Use of
diuretic, indapamide, plus, if needed, angiotensin converting enzyme inhibitors (ACEI), perindopril
As Treatment, Chronic
Is better Than
placebo
To reduce mortality, cardiovascular mortality and stroke (absolute risk reduction not reported in abstract)