aldosterone blockers, eplerone, 25 mg/day initiated 3 to 14 days after AMI
DISEASE INTERVENTION COMPARISON RESULTS
J Am Coll Cardiol. 2005 Aug 2;46(3):425-31 Randomized Controlled Trial, Multicenter Study
IN heart failure, acute, coronary disease, myocardial infarction The Use of
aldosterone blockers, eplerone, 25 mg/day initiated 3 to 14 days after AMI
As Treatment, Chronic
Is better Than
placebo
To reduce at 30 days all-cause mortality (3.2% with eplerone VS 4.6% with placebo), reduce cardiovascular mortality and reduce hospitalizations.