adjuvant chemotherapy after curative resection with oxiplatin added to fluorouracil plus leucovorin alone
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2004 Jun 3;350(23):2343-51 Randomized Controlled Trial, Multicenter Study
IN cancer, colorectal, adjuvant treatment The Use of
adjuvant chemotherapy after curative resection with oxiplatin added to fluorouracil plus leucovorin alone
As Treatment, Acute
Is better Than
adjuvant chemotherapy with fluorouracil plus leucovorin alone
To improve (moderately) the rate of disease-free survival at 3 years: 78.2% in intv. VS 72.9% in ctrl. No significative increase of adverse effects.