addition of biphasic or prandial rapid (aspart) insulin to oral agents
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2007 Oct 25;357(17):1716-30 Randomized Controlled Trial
IN diabetes mellitus, type 2, needing insulin The Use of
addition of biphasic or prandial rapid (aspart) insulin to oral agents
As Treatment, Chronic
Is better Than
addition of basal slow (detemir) insulin to oral agents
To improve glycaemic control: 7.2% in prandial group VS 7.6% in the basal group, but increased hypoglycaemia and weight gain.