a score combining: number of drugs and a history of adverse drug reaction as the strongest predictors, followed by heart failure, liver disease, presence of 4 or more conditions, and renal failure
DISEASE INTERVENTION COMPARISON RESULTS
Arch Intern Med. 2010 Jul 12;170(13):1142-8 Cohorts
IN elder patients, geriatric pharmacology, drug adverse effects The Use of
a score combining: number of drugs and a history of adverse drug reaction as the strongest predictors, followed by heart failure, liver disease, presence of 4 or more conditions, and renal failure
As Etiologic risk factor
Is useful Than
no systematized evaluation
To predict the risk of an adverse drug reaction: from 2% if 0-1 points to 25% when all factors present (8 points or more). The number of drugs were the most important single factor: risk doubled when => 5 drugs used, quadrupled when => 8 drugs