a combination of prednisone, azathioprine, and N-acetylcysteine
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2012 May 24;366(21):1968-77 Randomized Controlled Trial, Multicenter Study
IN pulmonary fibrosis, idiopathic The Use of
a combination of prednisone, azathioprine, and N-acetylcysteine
As Treatment, Chronic
Is worse Than
placebo
To modify the outcomes : combination-therapy group, as compared with the placebo group, had an increased rate of death (8 vs. 1%) and hospitalization (23 vs. 7%)