6-mo course of alternating corticosteroids (prednisolone) and cyclophosphamide
DISEASE INTERVENTION COMPARISON RESULTS
J Am Soc Nephrol. 2007 Jun;18(6):1899-904 Randomized Controlled Trial
IN nephrotic syndrome, idiopathic membranous nephropathy The Use of
6-mo course of alternating corticosteroids (prednisolone) and cyclophosphamide
As Treatment, Acute
Is better Than
supportive treatment only
To achieve initial complete remission (32% pred/cyclo VS 11% controls) and reduce need for dyalisis at 10 years (11% pred/cyclo VS 35% controls)