(moderately) intensive glucose control using insulin or oral hypoglycemic agents, sulfonylurea, metformin
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2008 Oct 9;359(15):1577-89 Randomized Controlled Trial, Multicenter Study
IN diabetes mellitus, type 2 The Use of
(moderately) intensive glucose control using insulin or oral hypoglycemic agents, sulfonylurea, metformin
As Treatment, Chronic
Is better Than
conventional treatment starting with diet
To reduce, at 10 years, any diabetes related point: 4.8% per year intensive VS 5.2% per year conventional (NNT 213). Also reduced mortality of any cause: 2.7%/year intensive VS 3.0%/year conventional (NNT 254)