coronary disease, myocardial infarction, heart failure, chronic, systolic
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2003 Nov 13;349(20):1893-906 Randomized Controlled Trial, Multicenter Study
IN coronary disease, myocardial infarction, heart failure, chronic, systolic The Use of
angiotensin II receptor blockers, valsartan, alone or combined with ACE inhibitors
As Treatment, Chronic
Is equal Than
angiotensin converting enzyme (ACE) inhibitors, captopril
To modify overall mortality (about 9.97% per year in valsartan, 9.75% per year in captopril and 9.63% per year with combined treatment) Combining valsartan + captopril did not increased survival but it did adverse events