cardiac arrest
DISEASE INTERVENTION COMPARISON RESULTS
JAMA. 2013 Jul 17;310(3):270-9 Randomized Controlled Trial, Multicenter Study
IN cardiac arrest, immediate resuscitation, post-resuscitation care The Use of
combined treatment with vasopressin (20 IU) plus epinephrine (1 mg) each 3 minutes for 5 times, plus 40 mg methylprednisolone IV once, plus hydrocortisone (300 mg/d for 7 days) in patients with shock after resuscitation
As Treatment, Acute
Is better Than
repeated epinephrine (1 mg) alone, without vasopressin nor corticosteroids
To improve survival to hospital discharge with no or little neurological impairment: 14% combined treatment VS 5% epinephrine alone
Arch Intern Med. 2000 Jul 10;160(13):1969-1973 Clinical Trial, Descriptive
IN cardiac arrest The Use of

As Prognostic Item
Is Than
To
N Engl J Med. 1993 Dec 23;329(26):1918-1921 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
Circulation. 1997 Feb 18;95(4):955-961 Randomized Controlled Trial, Multicenter Study
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
J Cardiothorac Vasc Anesth.1996(Feb);10(2):178-186 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
JAMA. 1994 May 11;271(18):1405-1411 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
JAMA. 1995 Apr 26;273(16):1261-1268 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
JAMA. 1996 May 8;275(18):1417-1423 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
Anasthesiol Intensivmed Notfallmed Schmerzther. 1994 Dec;29(8):492-500 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
Med Klin (Munich). 1997 Jul 15;92(7):381-8 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
N Engl J Med. 1999 Aug 19;341(8):569-75 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
Resuscitation. 1999 Aug;41(3):249-56 Meta-Analysis
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
Resuscitation. 1999 Nov;42(3):163-72 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
Resuscitation. 1998 May;37(2):119-25 Controlled Clinical Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
Resuscitation. 1996 Dec;33(2):125-134 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is Than
To
J Am Coll Cardiol. 1994 Jul;24(1):201-209 Randomized Controlled Trial
IN cardiac arrest The Use of
active compression-decompression
As Treatment, Acute
Is better Than
standard manual chest compression
To improve return of spontaneous circulation and 24-h survival, but not survival to hospital discharge
N Engl J Med. 1998 Nov 26;339(22):1595-601 Randomized Controlled Trial
IN cardiac arrest The Use of
adrenalina altas dosis
As Treatment, Acute
Is Than
To
JAMA. 1992 Nov 18;268(19):2667-2672 Randomized Controlled Trial
IN cardiac arrest The Use of
adrenalina altas dosis
As Treatment, Acute
Is Than
To
N Engl J Med. 2000 May 25;342(21):1546-53 Randomized Controlled Trial
IN cardiac arrest The Use of
chest compression alone
As Treatment, Acute
Is equal Than
chest compression plus mouth-to-mouth ventilation
To survival to hospital discharge (14.6% intv. vs 10.4% ctrl.), difference not statistically significant.
Arch Intern Med. 1994 Nov 14;154(21):2433-2437 Clinical Trial, Retrospective
IN cardiac arrest The Use of
decidiendo parar rcp
As Treatment, Acute
Is Than
To
Br Heart J. 1994 Nov;72(5):408-412 Cohorts, Retrospective
IN cardiac arrest The Use of
out-of-hospital cardiopulmonary resuscitation initiated by a bystander
As Treatment, Acute
Is better Than
waiting for trained medical team
To improving survival to hospital discherge (25% VS 8%) and reducing cerebral damage.
N Engl J Med. 2004 Jan 8;350(2):105-13 Randomized Controlled Trial
IN cardiac arrest The Use of
vasopressin IV
As Treatment, Acute
Is better Than
epinephrine IV
To improving survival to hospital discharge (4.7% intv. VS 1.5% ctrl.) among patients with asystole. There were no differences in patients with ventricular fibrillation or pulseless electrical activity.
Crit Care Med. 2005 Feb;33(2):414-8 Meta-Analysis
IN cardiac arrest, post-resuscitation care The Use of
hypothermia, mild, immediatly after resuscitation
As Treatment, Acute
Is better Than
normothermia
To reduce death at 6 months (RR 1,44) and improve neurological recovery (RR 1,68; NNT 4 - 13)
N Engl J Med. 2002 Feb 21;346(8):549-56 Randomized Controlled Trial, Multicenter Study
IN cardiac arrest, ventricular fibrillation The Use of
hypothermia, mild, immediatly after resuscitation
As Treatment, Acute
Is better Than
standard treatment with normothermia
To reduce mortality at 6 months (41% with hypothermia VS 55% if not)
N Engl J Med. 2008 Jan 3;358(1):9-17 Cohorts
IN cardiac arrest, ventricular fibrillation, in hospital The Use of
rapid defibrillation in less than 2 minutes
As Treatment, Acute
Is better Than
delayed defibrillation in more than 2 minutes
To increase survival to hospital discharge: 39% if in < 2 min VS 22% if not)
N Engl J Med. 1999 Sep 16;341(12):871-8 Randomized Controlled Trial
IN cardiac arrest, ventricular fibrillation, taquicardia ventricular The Use of
amiodarona
As Treatment, Acute
Is Than
To
Neurology. 2006 Jul 25;67(2):203-10 Systematic Review
IN coma, post-cardiac arrest, post-resuscitation care The Use of
several predictors: pupillary light response, corneal reflexes, motor responses to pain, myoclonus status epilepticus, serum neuron-specific enolase, and somatosensory evoked potential studies
As Diagnostic Tool
Is better Than
others clinical, biological and radiological findings
To accurately predict poor outcome in comatose patients after cardiopulmonary resuscitation