cancer, lung
DISEASE INTERVENTION COMPARISON RESULTS
Chest. 2000 Mar;117(3):773-8 Diagnostic
IN cancer, lung The Use of
estadiaje, tomografía de emisión de positrones, pet
As Diagnostic Tool
Is Than
To
Cochrane Database Syst Rev. 2000;2(2):CD002139 Systematic Review, Cochrane Review
IN cancer, lung, non-small cell The Use of
chemotherapy containing cisplatin
As Treatment, Acute
Is better Than
only supportive care, only surgery or only radiotherapy
To modestly improve survival: 10% absolute reduction of death at 1 year vs only supportive care
N Engl J Med. 2000 Jul 27;343(4):254-61 Diagnostic, Prospective
IN cancer, lung, non-small-cell The Use of
estadiaje, tomografía de emisión de positrones, pet
As Diagnostic Tool
Is Than
To
N Engl J Med. 2002 Jan 10;346(2):92-8 Randomized Controlled Trial, Multicenter Study
IN cancer, lung, non-small-cell The Use of
quimioterapia, cisplatino, carboplatino
As Treatment, Acute
Is Than
To
N Engl J Med. 2010 Jun 24;362(25):2380-8 Randomized Controlled Trial, Multicenter Study
IN cancer, lung, non-small-cell, advanced The Use of
gefitinib, EGFR tyrosine kinase inhibitor
As Treatment, Acute
Is better Than
carboplatin-paclitaxel chimiotherapy
To improve survival: 30 months gefitinib VS 24 carboplatin. Gefitinib had also less severe adverse effects.
N Engl J Med. 2010 Aug 19;363(8):733-42 Randomized Controlled Trial, Multicenter Study
IN cancer, lung, non-small-cell, advanced The Use of
early palliative care, integrated with standard oncologic care
As Treatment, Chronic
Is better Than
standard oncologic care alone
To improve quality of life and to improve survival (12 months early palliative VS 9 months standard) despite receiving less agressive end-of-life care.