atherosclerosis, coronary disease, ischemic stroke, high or normal cholesterol
DISEASE INTERVENTION COMPARISON RESULTS
J Am Coll Cardiol. 2005 Nov 15;46(10):1855-62. Epub 2005 Oct 24 Meta-Analysis
IN atherosclerosis, coronary disease, ischemic stroke, high or normal cholesterol The Use of
statins
As Treatment, Chronic
Is equal Than
interventions to primarily lower LDL cholesterol, if equal reduction
To The regression lines for non-statin and statin trials were similar and consistent with a one-to-one relationship between LDL-cholesterol lowering and coronary disease and stroke reduction.
Lancet. 2005 Oct 8;366(9493):1267-78. Epub 2005 Sep 27 Meta-Analysis
IN atherosclerosis, coronary disease, ischemic stroke, high or normal cholesterol The Use of
statins
As Treatment, Chronic
Is better Than
placebo
To reduce coronary and all-cause mortality (RRR 12%), and reduce major vascular events (vascular death, infarction, revascularization or stroke): RRR 21%.