atherosclerosis, coronary disease, ischemic stroke
DISEASE INTERVENTION COMPARISON RESULTS
J Am Coll Cardiol. 2002 Oct 16;40(8):1408-13 Cohorts
IN atherosclerosis, coronary disease, ischemic stroke The Use of
chronic infections, sropositivity to helicobacter pylori, clamidia pneumoniae, citomegalovirus
As Prognostic Item
Is useless Than
-
To predict risk for cardiovascular disease
J Am Coll Cardiol. 2005 Nov 15;46(10):1855-62. Epub 2005 Oct 24 Meta-Analysis
IN atherosclerosis, coronary disease, ischemic stroke, high or normal cholesterol The Use of
statins
As Treatment, Chronic
Is equal Than
interventions to primarily lower LDL cholesterol, if equal reduction
To The regression lines for non-statin and statin trials were similar and consistent with a one-to-one relationship between LDL-cholesterol lowering and coronary disease and stroke reduction.
Lancet. 2005 Oct 8;366(9493):1267-78. Epub 2005 Sep 27 Meta-Analysis
IN atherosclerosis, coronary disease, ischemic stroke, high or normal cholesterol The Use of
statins
As Treatment, Chronic
Is better Than
placebo
To reduce coronary and all-cause mortality (RRR 12%), and reduce major vascular events (vascular death, infarction, revascularization or stroke): RRR 21%.
Arch Intern Med. 2007 Jun 11;167(11):1122-9 Cohorts
IN atherosclerosis, coronary disease, ischemic stroke, peripheral arterial disease The Use of
chronic kidney disease measures (anemia, microalbuminuria, and GFR of <60 mL/min)
As Etiologic risk factor
Is useful Than
added to classical vascular risk factors
To idependently predict the risk of cardiovascular disease: OR about 1.30 for each one of the 3 measures, OR 1.98 for chronic kidney disease.
BMJ. 2002 Jan 12;324(7329):71-86 Meta-Analysis
IN atherosclerosis, coronary disease, ischemic stroke, peripheral arterial disease The Use of
antiplatelet drugs, aspirin, low-dose (75-150 mg/d), adenosine diphosphate (ADP) receptor inhibitors, clopidogrel
As Treatment, Chronic
Is better Than
placebo
To reduce recurrence of ischemic coronary and cerebral events, with absolute reductions of 3 to 4%, depending on specific conditions