antihypertensive drugs, angiotensin converting enzyme (ACE) inhibitors, adverse effects, congenital malformations
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2006 Jun 8;354(23):2443-51 Cohorts
IN antihypertensive drugs, angiotensin converting enzyme (ACE) inhibitors, adverse effects, congenital malformations The Use of
angiotensin converting enzyme (ACE) inhibitors during pregnancy, first trimester
As Treatment, Chronic
Is worse Than
other antihypertensive drugs
To increase the risk of major congenital malformations (RR, 2.71; 95 %CI, 1.72 to 4.27) as compared with no exposure to antihypertensive medications.