anticoagulants, vitamin K antagonists, atrial fibrillation, periprocedure interruption of anticoagulation
DISEASE INTERVENTION COMPARISON RESULTS
N Engl J Med. 2015 Aug 27;373(9):823-33 Randomized Controlled Trial, Multicenter Study
IN anticoagulants, vitamin K antagonists, atrial fibrillation, periprocedure interruption of anticoagulation The Use of
no bridging anticoagulation, just stopping warfarin 5 days before the procedure and resuming it within 24 hours afterwards
As Treatment, Acute
Is better Than
bridging anticoagulation with full-dose low-molecular-weight heparin (LMWH)
To avoid major bleeding (1.3% just stop Vs 3.2% bridging) while having similar incidence of arterial thromboembolism (0.4% just stop VS 0.3% bridging)