anticoagulants, oral direct thrombin inhibitors, dabigatran, oral factor Xa inhibitors, apixaban, rivaroxaban, edoxaban
DISEASE INTERVENTION COMPARISON RESULTS
Gastroenterology. 2013 Jul;145(1):105-112.e15 Systematic Review
IN anticoagulants, oral direct thrombin inhibitors, dabigatran, oral factor Xa inhibitors, apixaban, rivaroxaban, edoxaban The Use of
these direct oral anticoagulants
As Treatment, Chronic
Is worse Than
warfarin
To cause a higher risk of gastrointestinal bleeding: OR 1.58 dabigatran, 1.48 rivaroxaban, 1.23 apixaban (non-significant), 0.31 edoxaban (non-significant for superiority)