epilepsy, generalized, focal, newly diagnosed (first tonic-clonic seizure)
DISEASE INTERVENTION COMPARISON RESULTS
J Neurol Neurosurg Psychiatry. 2011 Aug;82(8):924-7 Randomized Controlled Trial, Multicenter Study
IN epilepsy, generalized, focal, newly diagnosed (first tonic-clonic seizure) The Use of
no treatment, unless seizure recurrs
As Treatment, Chronic
Is equal Than
starting treatment immediatly (carbamazepine, phenytoin, phenobarbital, or sodium valproate)
To modify mortality at 20 years: 10% no Tt VS 9% immediate Tt. Only the presence of aetiological factors for epilepsy predicted a higher mortality (HR 3.4). Most patients died from remote, non primarily neurological diseases.